Search on: CYTOCHROME-C OXIDASE 
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Descriptor English:   Electron Transport Complex IV 
Descriptor Spanish:   complejo IV de transporte de electrones 
Descriptor Portuguese:   Complexo IV da Cadeia de Transporte de Elétrons 
Synonyms English:   Cytochrome Oxidase
Cytochrome Oxidase Subunit III
Cytochrome a,a3
Cytochrome aa3
Cytochrome c Oxidase
Cytochrome c Oxidase Subunit III
Cytochrome c Oxidase Subunit IV
Cytochrome c Oxidase Subunit VIa
Cytochrome-c Oxidase
Cytochrome-c Oxidase (Complex IV)
Cytochrome-c Oxidase Subunit III
Cytochrome-c Oxidase Subunit IV
Ferrocytochrome c Oxygen Oxidoreductase
Heme aa3 Cytochrome Oxidase
Oxidase, Cytochrome
Oxidase, Cytochrome-c
Pre-CTOX p25
Signal Peptide p25 Subunit IV Cytochrome Oxidase
Signal Peptide p25-Subunit IV Cytochrome Oxidase
Subunit III, Cytochrome Oxidase
p25 Presequence Peptide Cytochrome Oxidase
p25 Presequence Peptide-Cytochrome Oxidase  
Tree Number:   D05.500.562.374
D08.811.600.250.687
D08.811.682.285
D12.776.157.530.450.250.875.304
D12.776.543.277.687
D12.776.543.585.450.250.875.484
Definition English:   A multisubunit enzyme complex containing CYTOCHROME A GROUP; CYTOCHROME A3; two copper atoms; and 13 different protein subunits. It is the terminal oxidase complex of the RESPIRATORY CHAIN and collects electrons that are transferred from the reduced CYTOCHROME C GROUP and donates them to molecular OXYGEN, which is then reduced to water. The redox reaction is simultaneously coupled to the transport of PROTONS across the inner mitochondrial membrane. 
Indexing Annotation English:   spell in titles & translations with lowercase c: cytochrome-c oxidase
Entry Combination - descr/qualif English:   Electron Transport Complex IV/deficiency use Cytochrome-c Oxidase Deficiency
 
See Related English:   Cytochrome-c Oxidase Deficiency
 
History Note English:   2004(1963); for SIGNAL PEPTIDE P25-SUBUNIT IV CYTOCHROME OXIDASE use CYTOCHROME C OXIDASE (NM) 1988-2001; for CYTOCHROME OXIDASE SUBUNIT III use CYTOCHROME C OXIDASE (NM) 1998-2001 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   31728 
Unique Identifier:   D003576 

Occurrence in VHL:
 

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